Clinical relevance and public health significance of hepatitis B virus genomic variations

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2009; 15(46): 5761-5769
Published online Dec 14, 2009. doi: 10.3748/wjg.15.5761

Table 2 HBV mutations associated with drug resistance

Nucleoside analogs	Mutations in the polymerase domains (amino acids)
Nucleoside analogs	A	B	C (YMDD)	D	E
Lamivudine/	-	V173L	M204I/V	-	-
Emtricitabine	-	L180M	M204I/V	-	-
Adefovir	-	A181V	I233V	N236T	-
Entecavir	-	I169T	S202I	M250V	-
Entecavir	-	T184G	S202I	M250V	-
Telbivudine	-	-	M204I	-	-
Famciclovir	-	L180M	-	-	-

-: Not reported.

Citation: Cao GW. Clinical relevance and public health significance of hepatitis B virus genomic variations. World J Gastroenterol 2009; 15(46): 5761-5769
URL: https://www.wjgnet.com/1007-9327/full/v15/i46/5761.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5761

Cao GW. Clinical relevance and public health significance of hepatitis B virus genomic variations. World J Gastroenterol 2009; 15(46): 5761-5769 [PMID: 19998495 DOI: 10.3748/wjg.15.5761]

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