Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population

Table 2 GST (M1, T1) genotypes in relation of GC risk stratified by some factors

	GSTM1 (null)		GSTT1 (null)
	OR (95% CI)	Pa	OR (95% CI)	Pa
All case	1.070 (0.935-1.224)		1.101 (0.963-1.259)
Smoking
Never smoker	0.994 (0.809-1.222)		1.099 (0.895-1.350)
Ever smoker	1.127 (0.938-1.355)	0.385	1.082 (0.901-1.299)	0.921
Drinking
Never drinkers	1.103 (0.916-1.328)		1.116 (0.927-1.344)
Current drinkers	1.019 (0.829-1.253)	0.559	1.077 (0.877-1.322)	0.748
Age (yr)
≤ 65 yr	1.069 (0.910-1.256)		1.129 (0.961-1.325)
> 65 yr	1.053 (0.823-1.348)	0.990	1.056 (0.825-1.352)	0.621
TNM stage
I+II	1.045 (0.900-1.214)		1.130 (0.974-1.312)
III+IV	1.050 (0.870-1.267)		1.044 (0.865-1.259)
Tumor site
Cardiac	1.200 (0.793-1.817)		1.030 (0.684-1.553)
Non-cardiac	1.060 (0.925-1.215)		1.100 (0.961-1.260)
Histological type
Intestinal	1.050 (0.892-1.235)		1.158 (0.984-1.362)
Diffuse	1.007 (0.830-1.220)		1.055 (0.871-1.278)
Mixed	1.210 (0.910-1.609)		0.975 (0.736-1.292)

Adjusted for age, sex; P^a for P interaction.