Impact of age-related comorbidity on results of colorectal cancer surgery

Table 1 Clinical and pathological data for group A (< 70 years) and B (≥ 70 years) n (%)

	Group A (n = 225)	Group B (n = 178)	P
Sex
Males	126 (56)	103 (57.9)	0.392
Females	99 (44)	75 (42.1)
Localization1
Colon	152 (67.6)	141 (79.2)	0.027
Rectum	71 (31.6)	35 (19.7)
Type of surgery
Elective	204 (90.7)	153 (86)	0.094
Emergency	21 (9.3)	25 (14)
Residual tumor
R0	174 (77.3)	137 (77)	0.512
R+	51 (22.7)	41 (23)
Comorbidity
Overall	104 (46.2)	123 (69.1)	0.0001
Cardiovascular diseases
Absent	156 (69.3)	87 (48.9)	0.0001
Present	69 (30.7)	91 (51.1)
Pulmonary diseases
Absent	217 (96.4)	164 (92.1)	0.048
Present	8 (3.6)	14 (7.9)
Diabetes mellitus
Absent	211 (93.8)	160 (89.9)	0.106
Present	14 (6.2)	18 (10.1)
Gastrointestinal diseases
Absent	198 (88)	158 (88.8)	0.470
Present	27 (12)	20 (11.2)
Other tumors
Absent	216 (96)	163 (91.6)	0.050
Present	9 (4)	15 (8.4)
Dukes’ stage
A	14 (6.2)	8 (4.5)	0.623
B	96 (42.6)	89 (50)
C	64 (28.4)	41 (23)
D	51 (22.7)	40 (22.5)
T stage
T1	18 (8)	10 (5.6)	0.485
T2	36 (16)	35 (19.7)
T3	148 (65.8)	110 (61.8)
T4	23 (10.2)	23 (12.9)
N stage
N0	122 (54.2)	110 (61.8)	0.270
N1	64 (28.4)	45 (25.3)
N2	39 (17.3)	23 (12.9)
Metastases
No	174 (77.3)	138 (77.5)	0.530
Yes	51 (22.7)	40 (22.5)

¹Synchronous localizations of colon and rectum are represented in two cases for each group (0.9% vs 1.1%).