Association between Helicobacter pylori seropositivity and digestive tract cancers

doi:10.3748/wjg.15.5465

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2009; 15(43): 5465-5471
Published online Nov 21, 2009. doi: 10.3748/wjg.15.5465

Table 2 Serum status of H pylori and CagA in cancer patients and control n (%)

	Cancer					Control
	Oral SCC	Esophageal SCC	Gastric cardia adenocarcinoma	Gastric non-cardia adenocarcinoma	Colon adenocarcinoma	1st hospital-based control	2nd hospital-based control	Community-based control
n	199	317	29	167	240	305	403	395
H pylori
-	104 (52.3)	205 (64.7)	8 (27.6)	48 (28.7)	105 (43.8)	141 (46.2)	164 (40.7)	235 (59.5)
+	95 (47.7)	112 (35.3)	21 (72.4)	119 (71.3)	135 (56.3)	164 (53.8)	239 (59.3)	160 (40.5)
CagA¹
-	14 (14.7)	8 (7.3)	1 (4.8)	9 (7.6)	12 (8.9)	24 (14.6)	-	11 (6.9)
±	13 (13.7)	10 (9.2)	3 (14.3)	8 (6.8)	7 (5.2)	14 (8.5)	-	6 (3.8)
+	68 (71.6)	91 (83.5)	17 (81.0)	101 (85.6)	116 (85.9)	126 (76.8)	-	142 (89.0)

¹CagA status was determined among the subjects with H pylori seropositivity (No CagA data was available in 3 esophageal SCC, 1 gastric non-cardia adenocarcinoma and 1 community-based control).

Citation: Wu IC, Wu DC, Yu FJ, Wang JY, Kuo CH, Yang SF, Wang CL, Wu MT. Association between Helicobacter pylori seropositivity and digestive tract cancers. World J Gastroenterol 2009; 15(43): 5465-5471
URL: https://www.wjgnet.com/1007-9327/full/v15/i43/5465.htm
DOI: https://dx.doi.org/10.3748/wjg.15.5465