Comorbidity negatively influences prognosis in patients with extrahepatic cholangiocarcinoma

Table 1 The Charlson comorbidity index (CCI)[12]

Weight1	Comorbid condition
1	Myocardial infarction
	Congestive heart failure
	Peripheral vascular disease
	Cerebrovascular disease (except hemiplegia)
	Dementia
	Chronic obstructive pulmonary disease
	Connective tissue disease
	Peptic ulcer disease
	Mild liver disease
	Diabetes (without complications)
2	Hemiplegia
	Moderate or severe renal disease
	Diabetes with end-organ damage (retinopathy, neuropathy, etc)
	Any second solid tumor (nonmetastatic), leukemia or lymphoma
3	Moderate or severe liver disease
6	Metastatic solid tumor
	AIDS

¹Optionally, the age index leads to adding 1 point for each decade over 40 years.