Do statins reduce hepatitis C RNA titers during routine clinical use?

Figure 3 Antiviral effects of individual HMG-CoA reductase inhibitors. A: Log HCV RNA viral load (IU/mL) for Group A subjects who received simvastatin (n = 42), lovastatin (n = 5), fluvastatin (n = 2) and pravastatin (n = 1); B: Log HCV RNA viral load (IU/mL) for simvastatin-exposed subjects who were receiving 10 mg (n = 4), 20 mg (n = 8), 40 mg (n = 20), 80 mg (n = 10). P-value obtained by Kruskal-Wallis Test; C: Pairwise comparison of median HCV RNA titers in lovastatin-exposed Group A subjects and Group B subjects who received lovastatin but were not being treated at the time of the RNA determination. P-value from Wilcoxon sign rank test.