Midkine translocated to nucleoli and involved in carcinogenesis

doi:10.3748/wjg.15.412

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Jan 28, 2009 (publication date) through May 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2009; 15(4): 412-416
Published online Jan 28, 2009. doi: 10.3748/wjg.15.412

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Figure 1 Subcellular localization analysis of MKS-GFP and MKN-GFP fusion proteins in carcinoma cell lines. MKS-GFP and MKN-GFP fusion proteins were localized to nuclei and accumulated in nucleoli, but rarely localized to cytoplasm. The high light “spots” in the center of nuclei are nucleoli. HepG2 cells (upper panel) and DU145 cells (bottom panel) are transfected with pEGFP-N2, and diffuse freely in the whole cell except in nucleoli.

Citation: Dai LC. Midkine translocated to nucleoli and involved in carcinogenesis. World J Gastroenterol 2009; 15(4): 412-416
URL: https://www.wjgnet.com/1007-9327/full/v15/i4/412.htm
DOI: https://dx.doi.org/10.3748/wjg.15.412