Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma

doi:10.3748/wjg.15.4952

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 21, 2009; 15(39): 4952-4957
Published online Oct 21, 2009. doi: 10.3748/wjg.15.4952

Table 2 Effects of genistein on cell cycle progression in the MHCC97-H cell line

Treatment (μg/mL genistein)	Cell cycle phase			Apoptosis (%)
Treatment (μg/mL genistein)	G₀/G₁ (%)	G₂/M (%)	S (%)	Apoptosis (%)
Control	59.12 ± 3.89	10.95 ± 6.41	29.93 ± 2.52	1.18 ± 0.01
5	67.86 ± 2.36^a	4.08 ± 1.82^a	28.06 ± 0.55	3.92 ± 1.63^a
10	69.53 ± 2.13^a	6.80 ± 0.48	23.65 ± 1.76^b	7.84 ± 1.72^b
20	71.85 ± 3.60^a	8.84 ± 4.07	19.31 ± 1.51^b	18.90 ± 4.98^b

^aP < 0.05,

^bP < 0.01 vs control. Cell cycle and apoptosis were evaluated by flow cytometric analysis on a FACScan cytofluorimeter. Values are mean ± SD from experiments.

Citation: Gu Y, Zhu CF, Dai YL, Zhong Q, Sun B. Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma. World J Gastroenterol 2009; 15(39): 4952-4957
URL: https://www.wjgnet.com/1007-9327/full/v15/i39/4952.htm
DOI: https://dx.doi.org/10.3748/wjg.15.4952