COX-2 polymorphisms -765G→C and -1195A→G and colorectal cancer risk

Table 1 Characteristics of patients with colorectal cancer (CRC) and controls (mean ± SD)

	Patients with CRC (n = 326)	Controls (n = 369)
Age (yr)	62.7 ± 11.7	64.5 ± 10.7
Male gender	195 (59.8%)	218 (59.1%)
Female gender	131 (40.2%)	151 (40.9%)
Localization of tumor1
Proximal2	101 (31.0%)
Distal3	222 (68.1%)

¹Note that the localization of the tumor was unknown in 3 patients;

²Proximal tumor: cecum, ascending and transverse colon;

³Distal tumor: descending colon, sigmoid, rectosigmoid junction and rectum.