Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009

Table 4 AJCC staging of ICC

Stage	Tumor	Node	Metastasis
I	T1	N0	M0
II	T2	N0	M0
IIIA	T3	N0	M0
IIIB	T4	N0	M0
IIIC	Any T	N1	M0
IV	Any T	Any N	M1

T1: Solitary tumor without vascular invasion; T2: Solitary tumor with vascular invasion or multiple tumors none > 5 cm; T3: Multiple tumors > 5 cm or tumor involving a major branch of the portal or hepatic vein(s); T4: Tumor(s) with direct invasion of adjacent organs other than the gallbladder or with perforation of visceral peritoneum; N0: No regional lymph node metastasis; N1: Regional lymph node metastasis; M0: No distant metastasis; M1: Distant metastasis. AJCC: American Joint Committee on Cancer; ICC: Intrahepatic cholangiocarcinoma.