Significance and relationship between Yes-associated protein and survivin expression in gastric carcinoma and precancerous lesions

Table 4 Correlation of survivin expression with clinicopathologic features of gastric carcinoma

Groups	n	Survivin expression				Positive (%)	χ²	P
		-	+	++	+++
Sex							4.87	0.172
Male	66	20	27	14	5	69.7
Female	32	14	7	6	5	56.2
Age							2.74	0.434
< 60	54	20	15	13	6	63.0
≥ 60	44	14	19	7	4	68.2
Gross type
EGC								0.3101
Type I + IIc	18	5	7	3	3	72.2
Type III	10	6	1	2	1	40.0
AGC								0.6961
Type BorI+ II	7	3	2	1	1	57.1
Type BorIII+ IV	62	19	24	14	5	69.4
WHO’s histological types							rk = 0.279	0.006
Well-diff. ade.	12	7	4	1	0	41.7		0.8241a
Moderately-diff. ade.	25	11	10	2	2	56.0		0.2231b
Poorly-diff. ade.	41	10	16	10	5	75.6		0.1491c
Undiff. ade.	2	1	1	0	0	50.0
Papillary ade.	2	1	0	1	0	50.0
Signet ring cell carcinoma	7	1	2	3	1	85.7
Mucinous ade.	9	3	1	3	2	66.7
Lauren types							8.61	0.035
Intestinal type carcinoma	39	19	14	4	2	51.3
Diffused type carcinoma	59	15	20	16	8	74.6
Lymph node metastasis								0.0051
Yes	52	12	19	15	6	76.9
No	17	10	7	0	0	41.2

¹Fisher’s exact test.

^aWell-diff. vs Moderately-diff. ade.;

^bModerately-diff. vs Poorly-diff. ade.;

^cWell-diff. vs Poorly-diff. ade..