Significance and relationship between Yes-associated protein and survivin expression in gastric carcinoma and precancerous lesions

Table 2 Correlation of YAP expression with clinicopathologic features of gastric carcinoma

Groups	n	YAP expression				Positive (%)		P
		-	+	++	+++
Sex								0.309
Male	66	31	22	8	5	53.0
Female	32	20	8	4	0	37.5
Age								0.304
< 60	54	30	15	8	1	45.5
≥ 60	44	21	15	4	4	51.2
Gross type
EGC								0.937
Type I + IIc	18	6	8	3	1	66.7
Type III	10	4	3	2	1	60.0
AGC								0.074
Type BorI + II	7	2	2	2	1	71.4
Type BorIII + IV	62	38	17	5	2	38.7
WHO’s histological types							rk = 0.181	0.079
Well-diff. ade.	12	8	4	0	0	33.3		0.635a
Moderately-diff. ade.	25	14	6	3	2	44.0		0.673b
Poorly-diff. ade.	41	17	15	6	3	58.5		0.406c
Undiff. ade.	2	2	0	0	0	0.0
Papillary ade.	2	0	1	1	0	100.0
Signet ring cell carcinoma	7	4	2	1	0	42.9
Mucinous ade.	9	6	2	1	0	33.3
Lauren types								0.669
Intestinal type carcinoma	39	23	11	4	1	41.0
Diffused type carcinoma	59	28	19	8	4	52.5
Lymph node metastasis								0.602
Yes	52	28	16	5	3	46.2
No	17	12	3	2	0	29.4

Fisher’s exact test. ade.: Adenocarcinomas; diff.: Differentiated; EGC: Early gastric carcinoma; AGC: Advanced gastric carcinoma.

^aWell-diff. vs Moderately-diff. ade.;

^bModerately-diff. vs Poorly-diff. ade.;

^cWell-diff. vs Poorly-diff. ade..