Effects of Chinese herbs on salivary fluid secretion by isolated and perfused rat submandibular glands

Table 1 Fluid secretion induced by CCh with/without Yin-nourishing CHs in SMG

Time (min)	YZ (n = 12)		SS (n = 12)		MD (n = 12)		TD (n = 10)
	FS (μL/g per min)	% of FS at 5 min	FS (μL/g per min)	% of FS at 5 min	FS (μL/g per min)	% of FS at 5 min	FS (μL/g per min)	% of FS at 5 min
(1) 4.95-5	63.8 ± 11.5	100.6 ± 0.5	69.4 ± 7.0	99.8 ± 0.4	68.3 ± 5.9	100.3 ± 0.3	64.7 ± 5.3	100.9 ± 0.4
(2) 19.95-20	65.3 ± 8.7	112.4 ± 6.3b	42.4 ± 3.4a	65.4 ± 6.4a	77.7 ± 3.8	122.0 ± 11.1a	62.0 ± 2.6	103.2 ± 11.6
(3) 24.95-25	67.0 ± 7.9	118.9 ± 8.1a	45.2 ± 3.4a	69.7 ± 6.7a	80.8 ± 4.1b	125.4 ± 9.3a	75.0 ± 2.8b	124.6 ± 13.9b
(4) 29.95-30	65.8 ± 7.5	117.7 ± 8.8b	40.6 ± 3.6a	62.8 ± 7.5a	80.7 ± 4.7b	123.6 ± 6.9a	77.0 ± 2.7a	127.6 ± 13.5b
(5) 34.95-35	67.9 ± 7.5	122.5 ± 10.2a	32.3 ± 4.9a	49.4 ± 8.3a	78.7± 5.3	119.2 ± 6.0a	75.4 ± 3.5b	125.3 ± 14.5b
(6) 9.95-10	-0.6 ± 0.4	-0.9 ± 1.1	0.8 ± 1.2	1.3 ± 1.7	0.1 ± 0.4	0.2 ± 0.6	-0.3 ± 0.5	-0.1 ± 1.1
(7) 14.95-15	-0.5 ± 1.4	-0.9 ± 3.4	-1.2 ± 0.5	-1.7 ± 0.5	-1.3 ± 0.81	-1.2 ± 1.2	-0.5 ± 0.3	-0.8 ± 0.4

Fluid secretion (FS) induced by (CCh) with/without Chinese herbs (CHs) in SMG. Fluid secretion was expressed in an absolute value (FS in μL/min per g wet weight of the gland) and % of the control value obtained at 5 min from the start of CCh perfusion (mean ± SE). n: The number of sampling points. Column (1) shows the average and SE from data set obtained at 4.95 and 5 min from the start of CCh application. Columns (2)-(5) show the values during addition of CH on CCh stimulation. Columns (6)-(7) show the values 5 min after CCh washing (6) and that under CH addition without CCh (7). t-tests between the control and the values at a fixed time during addition of CH on CCh stimulation are shown. The control and the values at a fixed time during addition of CH on CCh stimulation are shown

^bP < 0.1,

^aP < 0.05 vs FS at 4.95-5 min. YZ: Yuzhu; SS: Shashen; MD: Maimendong; TD: Tianmendong.