Anti-microbial antibodies in celiac disease: Trick or treat?

Table 3 Association between the titer of anti-microbial antibodies and the leading clinical symptoms at the time of celiac disease presentation (in Group 1, n = 78¹)

	Malabsorption	Non-specific gastrointestinal	Anaemia
n	32	34	9
gASCA IgG	54.8 (16.4-99.4)b	21.3 (7.1-76.5)	12.2 (8.8-36.7)
AMCA IgG	90.3 (59.5-115.9)b	73.8 (52.3-104.4)a	44.1 (25.1-55.0)
ALCA IgG	20.6 (16.7-31.2)b	23.7 (16.5-39.1)a	12.8 (9.9-15.2)
ACCA IgA	103.8 (53.3-192.1)b	57.3(37.4-100.5)a	26.8 (12.7-53.6)
OMP IgA	14.8 (5.2-33.2)	15.2 (8.2-24.2)	16.2 (2.9-34.1)

¹Detailed clinical data were not available for 4 patients, data of 3 patients with other symptoms are not shown;

^aP < 0.005,

^bP < 0.01, between patients with non-specific gastrointestinal symptoms or malabsorption and anaemia by t-test for independent samples with separate variance estimates.