Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence

Figure 2 Clustering of cirrhosis samples from transcript levels. Every transcript was measured by microarray and expressed as a [level per patient/median level in CLs]. The samples are shown as a dendrogram on top and the transcripts are listed vertically. Bottom scale bar (log2 scale): decreased (green), increased (red) or unchanged (black) transcript level. A: UHC was made in 14 HCC-free cirrhosis samples and eight CLs, from 70 altered transcript levels first identified as markers of HCC-free cirrhosis. A or V, alcoholism-related or HCV-related etiology; B: UHC was made in 20 HCC-associated cirrhosis samples and eight CLs, from five transcript levels identified by t-test adjusted by Bonferroni's correction. PA or PV, perinodular cirrhosis, with an alcoholism-related or HCV-related etiology, respectively.