Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2009; 15(3): 300-309
Published online Jan 21, 2009. doi: 10.3748/wjg.15.300

Table 4 Over-representation of functional subsets in our list of 70 transcripts

Cell proliferation¹(O = 7; E = 2.66; P = 0.01²)	Regulation of cell migration (O = 2; E = 0.15; P = 0.009)	Blood vesseldevelopment (O = 3; E = 0.41; P = 0.007)	Lipid metabolism (O = 9; E = 3.55; P = 0.007)	Antigen processing and presentation (O = 3; E = 0.25; P = 0.001)	Acute inflammatory response (O = 4; E = 0.58; P = 0.002)	NADH dehydrogenase activity (O = 3; E = 0.36; P = 0.005)	Oxidoreductaseactivity (O = 3; E = 0.25; P = 0.001)
JAG1 (Hs.590881³)	JAG1 (Hs.590881)	JAG1 (Hs.590881)	CLU (Hs.436657)	HLA-A (Hs.181224)	CLU (Hs.436657)	NDUFA6 (Hs.274416)	CYP2E1 (Hs.12907)
IGFBP7 (Hs.479808)	PLG (Hs.143436)	PLG (Hs.143436)	CYP2J2 (Hs.152096)	HLA-B (Hs.77961)	ORM1 (Hs. 567311)	NDUFB10 (Hs.513266)	CYP2J2 (Hs.152096)
IL12RB2 (Hs.479347)		CUL7 (Hs.520136)	CYP3A4 (Hs.567254)	CD74 (Hs.591258)	ORM2 (Hs.522356)	NDUFS4 (Hs.528222)	CYP3A4 (Hs.567254)
PLG (Hs.143436)			HMGCS2 (Hs.59889)		STAT3 (Hs.463059)
TIMP1 (Hs.522632)			APOB (Hs.120759)
ARHGEF1 (Hs.438429)			HSD17B6 (Hs.524513)
CD74 (Hs.591258)			DPM1 (Hs.301898)
			LARGE (Hs.474667)
			CD74 (Hs.591258)

¹This transcript subset coding for proteins with a related function was identified by gene ontology with the GOTM tool;

²Significance of enrichment for the GO category between transcript number observed (O) and expected (E) in this cate gory;

³Hs. number: Unique transcript identifier.

Citation: Caillot F, Derambure C, Bioulac-Sage P, François A, Scotte M, Goria O, Hiron M, Daveau M, Salier JP. Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence. World J Gastroenterol 2009; 15(3): 300-309
URL: https://www.wjgnet.com/1007-9327/full/v15/i3/300.htm
DOI: https://dx.doi.org/10.3748/wjg.15.300

Caillot F, Derambure C, Bioulac-Sage P, François A, Scotte M, Goria O, Hiron M, Daveau M, Salier JP. Transient and etiology-related transcription regulation in cirrhosis prior to hepatocellular carcinoma occurrence. World J Gastroenterol 2009; 15(3): 300-309 [PMID: 19140229 DOI: 10.3748/wjg.15.300]

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