Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD

doi:10.3748/wjg.15.3643

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2009; 15(29): 3643-3648
Published online Aug 7, 2009. doi: 10.3748/wjg.15.3643

Table 4 Association between (-670 A/G) Apo1/Fas gene polymorphism and location of lesion

ApoI/Fas	UC (n = 59)				CD (n = 105)
	G/G	G/A	A/A		G/G	G/A	A/A
Distal	4	9	8	Ileum	5	10	12^a
Left-sided olitis	5	15	6	Colon	13^b	8	3
Pancolitis	3	8	1	Ileocolon	16	22	16

^aχ² test between AA genotype and ileum location of lesion in CD patients (χ² = 3.89, two degrees of freedom, P corrected = 0.048) odds ratio is 2.48 (0.90 < OR < 6.87, CI = 95%);

^bχ² test between GG genotype and colon location of lesion in CD patients (χ² = 6.74, two degrees of freedom, P corrected = 0.009) odds ratio is 3.38 (1.19 < OR < 9.67, CI = 95%).

Citation: Ben Aleya W, Sfar I, Mouelhi L, Aouadi H, Makhlouf M, Ayed-Jendoubi S, Matri S, Filali A, Najjar T, Ben Abdallah T, Ayed K, Gorgi Y. Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD. World J Gastroenterol 2009; 15(29): 3643-3648
URL: https://www.wjgnet.com/1007-9327/full/v15/i29/3643.htm
DOI: https://dx.doi.org/10.3748/wjg.15.3643