Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn’s disease

Figure 1 Association between disease location (A), perianal disease (B), early azathioprine/biological therapy use (C) or smoking (D) and disease behavior change from non-stricturing, non-penetrating to complicated disease behavior in Crohn’s disease.