Portal hypertension secondary to myelofibrosis with myeloid metaplasia: A study of 13 cases

Table 1 Clinical characteristics, presentation and laboratory values within 1 wk of PH diagnosis for the 13 patients

Variable
Age (yr), median (range)
All patients	67 (49-88)
At time of diagnosis of MMM	61 (45-79)
At time of diagnosis of PH	66 (47-84)
Interval till presentation with PH	5 (1-11)
Sex n (%)
Male	9 (69)
Female	4 (31)
Type of MMM n (%)
AMM	6 (46)
PPMM	6 (46)
PETMM	1 (8)
Initial presentation n (%)
GI bleeding only	3 (23)
Ascites only	3 (23)
GI bleeding and ascites concurrently	2 (15)
Jaundice (with GI bleeding)	1 (8)
Encephalopathy	0 (0)
Abdominal pain (with ascites)	1 (8)
Splenomegaly	13 (100)
Hepatomegaly	9 (69)
Portal vein thrombosis	3 (23)
CBC, median (range)
Hemoglobin (g/dL)	10 (6.6-13.9)
WBC (× 109/L)	8.8 (2.1-49)
Platelet count (× 109/L)	225 (47-694)
Liver function, median (range)
AST (U/L)	69 (26-172)
Alkaline phosphatase (U/L)	338 (74-850)
Total bilirubin (mg/dL)	0.9 (0.3-2.2)
PT (s)	12.4 (10.8-14.1)
Albumin (g/dL)	4 (2.8-4.4)
SAAG	2 (1.9-2.4)

PT: Prothrombin time.