Clinicopathological analysis of paraganglioma with literature review

Table 3 Pheochromocytoma of the adrenal gland scoring scale (PASS)[22]

Feature	Score if present (No. of points assigned)
Large nests or diffuse growth (> 10% of tumor volume)	2
Central (middle of large nests) or confluent tumor necrosis (not degenerative change)	2
High cellularity	2
Cellular monotony	2
Tumor cell spindling (even if focal)	2
Mitotic figures > 3/10 HPF	2
Atypical mitotic figure(s)	2
Extension into adipose tissue	2
Vascular invasion	1
Capsular invasion	1
Profound nuclear pleomorphism	1
Nuclear hyperchromasia	1
Total	20

HPF: High-power field.