Nanosized As2O3/Fe2O3 complexes combined with magnetic fluid hyperthermia selectively target liver cancer cells

Table 4 Results of acute toxicity test of Fe₂O₃

Groups	Dose (g/kg)	Log	N	Deaths (N)	Mortality % (p)	Survival % (q)	p×q
1	10.00	1.000	10	10	100	0	0.00
2	7.07	0.849	10	4	40	60	0.24
3	5.00	0.699	10	4	40	60	0.24
4	3.50	0.544	10	2	20	80	0.16
5	2.50	0.398	10	0	0	100	0.00
6	1.75	0.243	10	1	10	90	0.09
7	1.25	0.097	10	0	0	100	0.00
	i = 0.15			∑p = 2.1

lgLD₅₀ = 1-0.15 (2.1-0.5) = 0.76, Sm = 0.04, Fe₂O₃ Lg LD₅₀ and its 95% CI: 0.76 ± 1.96 × 0.04 = 0.76 ± 0.079, Fe₂O₃ LD₅₀ and its 95% CI: 5.75 g/kg (4.80-6.90 g/kg).