Efficacy of the revised Vienna Classification for diagnosing colorectal epithelial neoplasias

Table 1 Relationship between the histopathologic diagnoses of cold biopsy specimens using the revised Vienna Classification and the depth of invasion in resected specimens of the same lesions

Invasion depth1	The revised Vienna Classification								Total (%)
	C1	C2	C3	C4.1	C4.2	C4.3	C4.4	C5
Non-N	2	0	0	0	0	0	0	0	2 (1.1)
LGIN	0	0	12	0	0	0	0	0	12 (6.7)
HGIN	0	0	16	2	1	0	2	0	21 (11.7)
Submucosa	0	0	2	1	0	3	8	4	18 (10.1)
MP or beyond	2	1	1	0	6	4	30	82	126 (70.4)
Total (%)	4 (2.2)	1 (0.6)	31 (17.3)	57 (31.8)				86 (48.0)	179 (100)

C: Category; Non-N: Non-neoplastic; LGIN: Low-grade intraepithelial neoplasia; HGIN: High-grade intraepithelial neoplasia; MP: Muscularis propria.

¹The histopathologic diagnoses of resected specimens were made using the World Health Organization classification. The comparison of two groups (intramucosal lesions (i.e. Non-N, LGIN and HGIN) versus submucosal invasive carcinomas) tested by Fisher’s exact test showed P = 0.01. The comparison of two groups (intramucosal lesions versus those that had invaded the submucosa or beyond) tested by Fisher’s exact test showed P < 0.001.