Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. May 7, 2009; 15(17): 2109-2115
Published online May 7, 2009. doi: 10.3748/wjg.15.2109
Figure 6
Figure 6 Effect of p90RSK on collagen type I promoter activity. HSCs transfected with the pAVU6-siRSK (bar 3, to decrease p90RSK expression), pMT2·RSK1 (bar 5, to increase p90RSK expression) showed no alteration of collagen type I promoter activity compared to control cells sham-transfected with pAVU6+27 (bar 4), pMT2 (bar 6), respectively. HSCs transfected with collagen type I luciferase reporter construct (bar 1) as normal control and Renilla luciferase expression construct (bar 2) as positive control. After 24 h incubation, the luciferase activity was determined. Data represent luciferase activity relative to the control (bar 1) and are expressed as mean ± SD of three separate experiments.