Clinical applications of hepatocyte transplantation

Table 1 Adult HT in metabolic liver disorders

	Patients (n = 27)	Range of viable1 cells number	Outcome (died/LT)	References
Urea cycle (OTC/ASL/ASS: 5/1/1)	7	1.9-4 × 109	1/4	[27–10]
Crigler-Najjar type 1	6	1.5-7.5 × 109	-/3	[11–14]
Hyper-cholesterolemia	5	1.0-3.2 × 109	-/-	[15]
Factor VII deficiency	3	1.1-2.2 × 109	-/2	[1116]
Others	62	3.2-7.5 × 109	-/3	[11171820]

¹In a few cases several cell infusions were performed; in one patient up to 18 infusions;

²Glycogenosis type 1 (n = 2); refsum disease (n = 1); progressive familial intra-hepatic cholestasis (n = 2); α-1-antitrypsine deficiency (n = 1).