In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleotide-loaded nanoparticles

doi:10.3748/wjg.15.1966

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Apr 28, 2009 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2009; 15(16): 1966-1972
Published online Apr 28, 2009. doi: 10.3748/wjg.15.1966

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Figure 2 Transduction and function of NANO-ASODNs in vitro. A: 0.2 &mgr;mol/L FAM-conjugated NANO-ASODNs transduced into HepG2 cells. The results were observed under a confocal microscope at indicted times of 6, 12 and 18 h; B: NANO-ASODNs down-regulated expression of MK mRNA; C: The proliferation of HepG2 cells was significantly inhibited by NANO-ASODNs.

Citation: Dai LC, Yao X, Wang X, Niu SQ, Zhou LF, Fu FF, Yang SX, Ping JL. In vitro and in vivo suppression of hepatocellular carcinoma growth by midkine-antisense oligonucleotide-loaded nanoparticles. World J Gastroenterol 2009; 15(16): 1966-1972
URL: https://www.wjgnet.com/1007-9327/full/v15/i16/1966.htm
DOI: https://dx.doi.org/10.3748/wjg.15.1966