Non-alcoholic steatohepatitis with normal aminotransferase values

Table 2 Features of NASH patients according to high and normal aminotransferase levels n (%)

	NASH cases (n = 23)		P
	Normal aminotransferase levels (n = 7)	Elevated aminotransferase levels (n = 16)
Age (yr)	52.8 ± 5.04	50.44 ± 5.12	> 0.05
Gender (male/female)	1/6 (14.2/85.8)	6/10 (37.5/62.5)	> 0.05
Hepatomegaly	2 (28.5)	5 (31.2)	> 0.05
BMI (kg/m2)
Normal weight	-	-
Overweight	-	-
Obese	6 (85.7)	14 (87.5)	> 0.05
Morbid obese	1 (14.3)	2 (12.5)	> 0.05
Waist/hip ratio	5 (71.4)	12 (75.0)	> 0.05
Systolic blood pressure (mmHg)1	130.0 (110-150)	120 (110-180)	> 0.05
Diastolic blood pressure (mmHg)1	80 (60-90)	70 (60-120)	> 0.05
Hypertension	3 (42.9)	7 (43.8)	> 0.05
HDL-Cholesterol (mg/dL)	43.86 ± 8.97	44.19 ± 4.07	> 0.05
Low-HDL level	4 (57.1)	9 (56.3)	> 0.05
Triglycerides (mg/dL)	183.57 ± 95.82	130.44 ± 59.46	> 0.05
Hypertriglyceridemia	5 (71.4)	5 (31.3)	> 0.05
Fasting glucose (mg/dL)1	101 (73-164)	102.83 (87-195)	> 0.05
Diabetes	2 (28.6)	4 (25.0)	> 0.05
Impaired glucose tolerance	3 (42.9)	6 (37.5)	> 0.05
Fasting insulin (&mgr;U/mL)	11.8	13.96	> 0.05
Insulin resistance-HOMA-IR	1 (14.3)	9 (56.3)	> 0.05
AST (IU/L)1	18 (14-29)	46 (33-92)	< 0.05
ALT (IU/L)1	21 (15-39)	77 (32-158)	< 0.05
GGT (IU/L)1	21 (15-33)	40 (16-119)	< 0.05
ALP (IU/L)1	96 (52-111)	78.5 (55-152)	> 0.05
Metabolic syndrome	6 (85.7)	12 (75.0)	> 0.05

¹Data expressed as median (minimum-maximum); BMI: Body mass index; HDL: High-density lipoprotein; ALP: Alkaline phosphatase; GGT: Gamma glutamyl transpeptidase. There was no difference between the features of NASH patients with high and normal aminotransferase levels.