Incidence and survival of stomach cancer in a high-risk population of Chile

Table 3 Factors associated with SC survival. Valdivia 1998-2002. Kaplan-Meier (n = 445 cases). Univariate analyses

Variable	n(%)	3-yr survival		5-yr survival		P-value 5-yr survival
		%	95% CI	%	95% CI
Sex
Female	120 (27.0)	20.3	13.0-27.6	12.9	6.7-19.1	-
Male	325 (73.0)	13.4	9.7-17.1	9.8	6.5-13.1	0.56
Age (yr)
< 55	81 (18.2)	21.0	12.1-29.9	17.3	9.1-25.5	0.037
55-79	300 (67.4)	15.5	11.3-19.7	9.9	6.4-13.4	0.006
> 80	64 (14.4)	6.3	0-12.8	4.2	0-9.7	-
Ethnic group
Mapuche1	76 (17.1)	7.3	1.2-13.4	4.4	0-9.2	-
Hispanic	369 (82.9)	16.9	13.0-20.8	11.9	8.5-15.3	0.02
School years
0 to 8	348 (83.6)	9.1	6.0-12.2	6.4	3.7-9.1	-
> 8	68 (16.4)	19.7	10.2-29.3	8.9	2.0-15.8	0.08
Home
Urban	248 (57.1)	18.7	13.8-23.6	12.9	8.6-17.2	0.006
Rural	186 (42.9)	10.6	6.1-15.1	8.2	4.1-12.3	-
Sign and symptoms at diagnosis
Supraclavicular adenopathy
Yes	28 (8.0)	0	-	0	-	-
No	321 (92.0)	18.6	14.3-22.9	13.8	9.9-17.7	0.00018
Palpable mass
Yes	52 (14.4)	8.7	1.0-16.4	6.2	0-13.1	-
No	310 (85.6)	17.8	13.5-22.1	13.0	9.2-16.8	0.00001
Ascitis
Yes	47 (13.0)	0	-	0	-	-
No	315 (87.0)	18.9	14.5-23.3	13.8	9.9-17.0	0.000002
GI bleeding
Yes	101 (22.7)	20.1	12.2-28.0	13.7	6.9-20.5	0.87
No	344 (77.3)	13.8	10.1-17.5	9.7	6.5-12.9	-
Vomiting
Yes	100 (22.5)	10.3	4.3-16.3	6.2	1.4-11.0	-
No	345 (77.5)	16.8	12.8-20.8	11.9	8.4-15.4	0.046
Weight loss
Yes	277 (62.2)	13.6	9.5-17.7	10.0	6.4-13.6	0.45
No	168 (37.8)	18.1	12.2-24.0	11.5	6.5-16.5	-
Abdominal distension
Yes	78 (17.5)	11.5	4.4-18.6	7.7	1.8-13.6	0.13
No	367 (82.5)	16.1	12.3-19.9	11.2	7.9-14.5
Pain
Yes	271 (60.9)	19.0	14.2-23.8	14.5	10.2-18.8	0.14
No	174 (39.1)	9.6	5.2-14.0	4.6	1.4-7.8
Months with symptoms
< 3	117 (32.3)	14.9	8.3-21.5	9.3	3.9-14.7
3 to 6	95 (26.2)	17.6	9.9-25.3	14.2	7.1-21.3	0.32
> 6	150 (41.4)	16.6	10.5-22.7	13.7	8.1-19.4	0.30
Gastrectomy
Yes	128 (28.8)	44.8	36.0-53.6	33.6	25.1-42.1	0.0000001
No	317 (71.2)	3.5	1.4-5.6	1.3	0-2.6	-
Surgical intention
Curative	89 (42.4)	50.4	39.9-60.9	38.6	28.3-48.9	0. 0000001
Palliative	121 (57.6)	14.4	5.8-23.0	10.4	2.6-18.2	-
Lauren class
Intestinal	220 (59.1)	21.0	15.5-26.5	14.6	9.8-19.4	0.0000003
Diffuse	152 (40.9)	11.2	6.1-16.3	7.0	2.9-11.1	-
Tumor
Localized	325 (91.0)	20.0	15.6-24.4	14.6	10.6-18.6	0.004
All stomach	32 (9.0)	0	-	0	-	-
Size
< 4 cm	16 (12.8)	67.0	43.3-90.7	60.0	35.1-84.9	-
4 to 9.9 cm	71 (56.8)	48.3	36.3-60.3	35.5	23.9-47.1	0.161
> 10 cm	38 (30.4)	29.0	15.6-43.4	21.1	8.1-34.1	0.006
Depth
Mucosa	9 (7.1)	100	-	100	-	-
Muscle/subserosa	7 (5.6)	85.7	59.8-100	71.4	37.9-100	0.14
Serosa	110 (87.3)	38.2	29.0-47.5	27.2	18.6-35.8	0.003
Lymphatic invasion stage
0	21 (17.8)	94.9	85.1-100	77.1	57.3-96.9	-
I	36 (30.5)	55.4	39.1-71.7	40.2	23.8-56.6	0.008
II	33 (28.0)	38.3	21.5-55.1	25.3	10.1-40.5	0.0005
III	28 (23.7)	10.7	0-22.2	10.7	0-22.2	0.00001
Metastasis
0	185 (47.0)	30.6	23.5-37.4	22.2	16.0-28.4	-
1	209 (53.0)	2.5	0.3-4.7	1.5	0-3.2	0.0000001
TNM
I	9 (2.1)	100	-	85.7	59.8-100	-
II	18 (4.1)	77.3	57.7-96.9	65.4	42.9-87.9	0.24
III	53 (12.1)	49.2	35.5-62.9	32.2	19.1-45.3	0.011
IV	281 (64.0)	3.0	1.0-5.0	2.2	0.4-4.0	0.00003
Unknown	78 (17.8)	12.3	4.9-19.7	3.8	0-8.3	0.00007

¹Native American Indian residents of southern Chile.