Melatonin ameliorates experimental hepatic fibrosis induced by carbon tetrachloride in rats

Table 4 Serum HA, LN and PIIINP levels in different groups (mean ± SD)

Group	Dose (mg/kg)	n	HA (&mgr;g/L)	LN (&mgr;g/L)	PIIINP (&mgr;g/L)
Normal	-	11	71.65 ± 27.64	37.65 ± 6.09	26.41 ± 7.28
Model	-	13	201.10 ± 68.46b	55.26 ± 12.30b	35.88 ± 5.92b
NAC	100	12	131.31 ± 58.58ac	48.28 ± 4.93b	32.89 ± 3.90b
MEL	2.5	11	174.41 ± 72.99b	48.15 ± 6.40b	34.21 ± 5.76b
	5	13	153.54 ± 86.19b	48.22 ± 9.51b	33.12 ± 4.71b
	10	12	135.71 ± 76.03ac	45.89 ± 11.71ac	31.99 ± 6.09a

HA: Hyaluronic acid; LN: Laminin; PIIINP: Procollagen III N-terminal peptide.

^aP < 0.05 vs normal control group;

^bP < 0.01 vs normal control group;

^cP < 0.05 vs model control group.