Intestinal permeability and its association with the patient and disease characteristics in Crohn&rsquo;s disease

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Mar 7, 2008; 14(9): 1399-1405
Published online Mar 7, 2008. doi: 10.3748/wjg.14.1399

Table 3 Relationship between intestinal permeability (log LMR) and characteristics of the patients and disease (n = 125)

Variables	n	Mean LMR (95% CI)	P value
Gender
Males	66	0.036 (0.029, 0.046)	0.0024^a
Females	59	0.022 (0.0178, 0.028)
Area of involvement of the GI tract^b
Small intestine only (L1)	16	0.028 (0.0175, 0.0447)	0.0001^a
Large Intestine only (L2)	62	0.021 (0.0174, 0.0255)
Ileo-colonic (L3)	47	0.0451 (0.0336, 0.0605)
UGI Involvement
Absent	102	0.0268 (0.0224, 0.0321)	0.0406^a
Present	23	0.0416 (0.027, 0.062)
Perianal disease
Absent	100	0.028 (0.023, 0.033)	0.3573
Present	25	0.0339 (0.0234, 0.049)
Behavior of the disease^d
Non-fistulizing Non-stricturing (B1)	74	0.024 (0.0194, 0.0298)	0.0062^a
Stricturing (B2)	37	0.043 (0.032, 0.058)
Fistulizing (B3)	14	0.028 (0.018, 0.042)
Extra intestinal manifestations
Absent	76	0.028 (0.0226, 0.034)	0.5674
Present	49	0.030 (0.0236, 0.040)

Values are expressed as geometric mean (95% CI),

^aP < 0.05; Large intestine only vs ileo-colonic,

^bP = 0.001 < 0.01; Non-fistulizing non-stricturing vs stricturing,

^dP = 0.004 < 0.01.

Citation: Benjamin J, Makharia GK, Ahuja V, Kalaivani M, Joshi YK. Intestinal permeability and its association with the patient and disease characteristics in Crohn’s disease. World J Gastroenterol 2008; 14(9): 1399-1405
URL: https://www.wjgnet.com/1007-9327/full/v14/i9/1399.htm
DOI: https://dx.doi.org/10.3748/wjg.14.1399

Benjamin J, Makharia GK, Ahuja V, Kalaivani M, Joshi YK. Intestinal permeability and its association with the patient and disease characteristics in Crohn’s disease. World J Gastroenterol 2008; 14(9): 1399-1405 [PMID: 18322955 DOI: 10.3748/wjg.14.1399]

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