Neuro-regulation of lower esophageal sphincter function as treatment for gastroesophageal reflux disease

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Feb 21, 2008 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2008; 14(7): 985-990
Published online Feb 21, 2008. doi: 10.3748/wjg.14.985

Table 1 Factors that regulate LES function

Factors that increase tLESRs	Factors that decrease tLESRs
Gastric distention	GABA agonists
Pharyngeal stimulation	Anticholinergics
High-fat meals	Opioid receptor agonists
CCK-A receptor agonists	Nitric oxide synthase inhibitors
	Endoscopic therapy
	Fundoplication

Citation: Sidhu AS, Triadafilopoulos G. Neuro-regulation of lower esophageal sphincter function as treatment for gastroesophageal reflux disease. World J Gastroenterol 2008; 14(7): 985-990
URL: https://www.wjgnet.com/1007-9327/full/v14/i7/985.htm
DOI: https://dx.doi.org/10.3748/wjg.14.985