Graft-verse-host disease after liver transplantation: A report of two cases and review of literature

Table 3 Treatment, time point of treatment and patient outcome

Case	Treatment	Time point of treatment after onset (d)	Outcome
1	Decreased immunosuppressant; G-CSF; IVIG	16	Death, infection
2	Decreased immunosuppressant; Methylprednisolone 80 mg × 10 d, then taper rapidly; G-CSF; IVIG	6	Death, gastrointestinal bleeding, infection, MOF
3	Decreased immunosuppressant; Methylprednisolone 80 mg × 10 d, then taper rapidly; G-CSF; ATG; IVIG	16	Death, gastrointestinal bleeding, infection, ARDS
4	Decreased immunosuppressant; Methylpredprednisolone impulse treatment, then taper; G-CSF	5	Death, gastrointestinal bleeding, infection, MOF
5	Discontinued immunosuppressant; Methylprednisolone impulse 480 mg/d, then taper; G-CSF; IVIG	6	Death, infection, gastrointestinal bleeding, respiratory failure
6	Non-specific treatment	?	Death, infection

G-CSF: Granulocyte colony-stimulating factor; IVIG: Intravenous immunoglobin therapy; MOF: Multiple organ failure; ARDS: Acute respiratory distress syndrome.