Diagnosis of Crohn’s disease in India where tuberculosis is widely prevalent

Table 3 Sensitivity, specificity and accuracy in diagnosis of CD or GITB

Parameters	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)
Factors predicting CD
Clinical score (fever, hematochezia, diarrhoea and duration of symptoms)	80.7	88.4	87.5	82.1	84.62
Co-existing deep linear/ serpiginous ulcers and/or Cobble-stone appearance	69.2	65.3	66.6	72	67.3
Pathologist reporting as IBD	38.4	88.4	76.9	58.9	63.4
Recurrence of disease after surgery	77.7	100	100	66.6	42.3
Factors predicting GITB
Co-existing pulmonary lesions and/or abdominal lymphadenopathy	57.6	88.4	83.3	67.6	73.1
Pathologist reporting as TB	50	100	100	66.6	75
Granuloma on histology	57.6	69.2	65.2	62	63.4
TB PCR positive	65.3	100	100	74.2	82.6
Smear and/or culture positive for AFB	23	100	100	56.5	61.5
Complete response to ATT	100	100	100	100	100