Severe acute pancreatitis: Pathogenetic aspects and prognostic factors

Table 2 Early predictors of severity

Marker		Period	Reference
Clinical:	Obesity	on admission	[111,112]
Radiological:	Abnormal chestradiograph	within 24 h	[21]
Laboratory:	Serum BUN	within the 1st 24 h	[104]
	Serum creatinine	within the 1st 24 h	[21]
	Hematocrit	on admission	[133]
	Proteinuria	2nd d of admission	[111]
	CRP	24-48 h	[129]
	MMP-9	1-48 h of admission	[132]
	SAA	within the 1st 24 h	[43]
	IL-6, IL-8	within the 1st 24 h	[10]
	IL-18	within the 1st 48 h	[28]
	Trypsinogen-2	on admission	[131]
	Trypsin-2 AAT	on admission	[131]
Factors (in biliary pancreatitis) predicting need for ICU:
	Heart rate, Glucose,
	BUN, WBC&CRP	on admission	[136]

CRP: C-reactive protein, MMP-9: Matrix metalloproteinase-9; SAA: Serum amyloid A; IL-6, 8, 18: Interleukins 6, 8 and 18; BUN: Blood urea nitrogen; WBC: White blood cell count, trypsin-2; AAT: Trypsin-2-alpha-1-antitrypsin.