Severe acute pancreatitis: Pathogenetic aspects and prognostic factors

Table 1 Predictors of severity of acute pancreatitis

Severity predictor	Reference
Multifactorial scoring system
Ranson, Imrie, APACHE II	[14]
Clinical data
Age	[108]
Etiology	[108]
Obesity	[63,109]
Simple prognostic scores
BUN (=/> 25 mg/dL), LDH (=/> 900 IU/L) and PN on CE-CT	[104]
Age, highest serum creatinine (within 72 h), chronic health status and requirement for mechanical ventilation	[119]
Inflammatory markers:
IL-6, IL-8	[10]
PL-A2, CRP	[64]
PMN-elastase	[122]
TAP	[123]
PCT	[124]
CT-scoring index (CTSI)	[140]

PN: Pancreatic necrosis; CE-CT: Contrast enhanced computed tomography; IL-6: Interleukin-6; IL-8: Interleukin-8; PL-A2: Pancreatic phospholipase A2; TAP: Trypsinogen activation peptide; CRP: C-rective protein; PTC: procalcitonin; PMN: Polymorphonuclear cells; LDH: Lactate dehydrogenase.