Disruption of colonic barrier function and induction of mediator release by strains of Campylobacter jejuni that invade epithelial cells

Figure 3 HCA-7 monolayer release of LDH, [³H] mannitol flux and release of IL8 and PGE2 after inoculation with different strains of C. jejuni. All data are mean ± SE at 4 h, (n = 4). A: Strain 2801055 showed a significantly higher LDH release after 4 h (^aP < 0.05) incubation compared to the other two strains, which were similar to control values; B: Strain 2801055 induced a significantly higher flux rate across the monolayer after 4 h (^aP < 0.05) incubation compared to the other two strains, which were similar to control values; C: Strain 2801055 showed a significantly higher IL8 release after 4 h (^aP < 0.05) incubation compared to the other two strains, which were similar to control values; D: Strain 2801055 showed a significantly higher PGE2 release after 4 h (^aP < 0.05) incubation compared to the other two strains, which were similar to control values.