©2008 The WJG Press and Baishideng.
World J Gastroenterol. Dec 14, 2008; 14(46): 7059-7067
Published online Dec 14, 2008. doi: 10.3748/wjg.14.7059
Published online Dec 14, 2008. doi: 10.3748/wjg.14.7059
Table 2 Molecular and functional expression of AQPs in cholestasis
| Experimental model | AQP8 | AQP9 | Ref. | ||||
| Protein | mRNA | CPM Pf | Protein | mRNA | BLM Pf | ||
| Obstructive cholestasis | |||||||
| BDL | ↓↓ | ↑ | ND | ↓↓↓ | ↓ | ↓ | [57,58] |
| Intracellular cholestasis | |||||||
| EE-induced cholestasis | ↓↓↓ | ↑ | ↓ | ↔ | ND | ND | [59] |
| LPS-induced cholestasis | ↓↓↓ | ↑ | ↓ | ↔ | ND | ND | [64] |
| CLP-induced cholestasis | ↓↓↓ | ND | ND | ↔ | ND | ND | [66] |
- Citation: Lehmann GL, Larocca MC, Soria LR, Marinelli RA. Aquaporins: Their role in cholestatic liver disease. World J Gastroenterol 2008; 14(46): 7059-7067
- URL: https://www.wjgnet.com/1007-9327/full/v14/i46/7059.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.7059