Editorial
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Nov 14, 2008; 14(42): 6437-6441
Published online Nov 14, 2008. doi: 10.3748/wjg.14.6437
Table 1 Pivotal chemotherapy trials in advanced HCC
ChemotherapyStudyNo. of patientsResponse rate
Doxorubicin
Pegylated liposomal doxorubicinHalm160
DoxorubicinJohnson3244
Doxorubicin, 5-FU, mitomycin CAl-Idrissi4013
Doxorubicin, bleomycinRavry6016
Doxorubicin, cisplatinLee3718.9
Doxorubicin, 5-FU, cisplatin, interferon (PIAF)Yeo9120.9
Cisplatin
CisplatinFalkson3517
Cisplatin, interferonJi3013.3
Cisplatin, 5-FU, mitoxantroneIkeda5127
Gemcitabine
GemcitabineFuchs300
GemcitabineYang2818
Gemcitabine, oxaliplatinTaieb2119
Epirubicin, etoposide
EpirubicinHochster1817
EtoposideMelia2413
Epirubicin, etoposideBobbio- Pallavicini3639
Others
MitoxantroneLai200
PaclitaxelChao200
IrofulvenFalcon- Lizaraso297
IrinotecanO'Reilly147
NolatrexedStuart268
T138067Leung2110
CapecitabinePatt3711
5-FU, interferonPatt2814