Secondary prevention of recurrence by interferon therapy after ablation therapy for hepatocellular carcinoma in chronic hepatitis C patients

Table 2 Univariate and multivariate analyses of the carcinogenic factors for HCC in male patients with HCV cirrhosis

		Univariate analysis			Multivariate analysis
Variables	Number of patients	P-value1	RR2	95% CI	P-value3	RR2	95% CI
Age (yr)
≥ 60	43	P = 0.032	1.726	1.032-2.881	P = 0.035	4.469	1.271-5.723
< 60	42		1			1
Alcohol
Yes	45	P = 0.826	1.058	0.632-1.771	NS (P = 0.676)	0.877	0.473-1.025
No	40		1			1
Smoking
Yes	36	P = 0.566	0.863	0.517-1.440	NS (P = 0.696)	0.893	0.504-1.580
No	49		1			1
AST
≥ 100	47	P = 0.213	1.376	0.824-2.298	NS (P = 0.151)	1.863	0.797-4.350
< 100	38		1			1
ALT
≥ 100	46	P = 0.805	1.064	0.643-1.763	NS (P = 0.485)	0.752	0.337-1.667
< 100	39		1			1
γ-GTP
≥ 80	41	P = 0.509	1.182	0.714-1.954	NS (P = 0.561)	1.178	0.679-2.041
< 80	44		1			1
Anti-HBc
Positive	43	P = 0.111	1.522	0.898-2.577	NS (P = 0.099)	1.609	0.914-2.835
Negative	42		1			1

¹P-values were obtained by using the log-rank test;

²RR were calculated by comparing classes with Cox regression analysis;

³P-values were obtained by using Cox regression analysis. RR: Relative risks; CI: Confidence interval; NS: Not significant.