Secondary prevention of recurrence by interferon therapy after ablation therapy for hepatocellular carcinoma in chronic hepatitis C patients

Table 1 Univariate and multivariate analyses on the carcinogenic factors for HCC in patients with HCV cirrhosis

		Univariate analysis			Multivariate analysis
Variables	Number of patients	P-value1	RR2	95% CI	P-value3	RR2	95% CI
Sex
Male	85	P= 0.001	1.971	1.298-2.991	P = 0.005	2.107	1.198-2.987
Female	80		1			1
Alcohol
Yes	49	P= 0.012	1.681	1.108-2.550	NS (P = 0.496)	1.234	0.673-2.262
No	116		1			1
ALT
≥ 100	77	P= 0.013	1.657	1.103-2.489	NS (P = 0.876)	1.050	0.572-1.927
< 100	88		1			1
LDH
≥ 480	74	NS (P= 0.064)	-	-	NS (P = 0.112)	0.673	0.413-1.096
< 480	91					1
HCV-RNA
≥ 1.0 Meq/mL	110	P= 0.018	1.709	1.086-2.695	P = 0.028	1.658	1.125-2.315
< 1.0 Meq/mL	55		1			1
Ant i-HBc
Positive	78	NS (P = 0.834)	-	-	NS (P = 0.577)	1.136	0.724-1.782
Negative	87					1

¹P-values were obtained by using the log-rank test;

²RR were calculated by comparing classes with Cox regression analysis;

³P-values were obtained by using Cox regression analysis. RR: Relative risks; CI: Confidence interval; NS: Not significant.