An effective vaccine against colon cancer in mice: Use of recombinant adenovirus interleukin-12 transduced dendritic cells

Figure 2 IL-12 production by the DCs transduced with AdVIL-12. BM-DCs was transduced with AdVIL-12 at various doses. DCs supernatant was examined 48 hrs later for the IL-12 production by ELISA, with nontransduced DCs was as control. Statistical analysis used the paired Student’s t test. Data are given as mean ± SE. ^aP < 0.05 AdVIL-12/DCs (MOI 100) compared with nontransduced DCs or AdVIL-12/DCs (MOI 50). 1: Nontransduced DCs. 2: AdVIL-12/DCs (MOI 50). 3: AdVIL-12/DCs (MOI 100). 4: AdVIL-12/DCs (MOI 300). 5: AdVIL-12/DCs (MOI 500).