Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells

Figure 4 Effect of Chaga extract on the protein levels of G₀/G₁ regulatory Cdks and cyclin in HepG2 cells. The effect of Chaga extract on the protein levels of G₀/G₁ regulatory Cdks and cyclin in HepG2 cells was determined by western blot. Western blot analysis for Cdks ( A: Cdk2, Cdk4, and Cdk6) and Cyclins ( B: Cyclin D1, Cyclin D2, and Cyclin E) was performed using specific antibodies with β-actin as a loading control.