Fibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ

Figure 1 Immunohistochemical analysis of hfgl2 prothrombinase and fibrin in tumor tissues. Fgl2 was verified by immunohistochemistry in colon cancer (A, × 400), esophageal cancer (B, × 200), gastric cancer (C, × 400), breast cancer (D, × 200), lung cancer (E, × 200) and cervix cancer (F, × 100). Fibrin deposition was stained for colon cancer (G, × 200). Dual staining of hfgl2 (indigo) and fibrin in colon cancer (H, × 1000) and cervix cancer (I, × 400) displayed the co-localization of hfgl2 (indigo) and fibrin (scarlet) expression. Cells expressed fgl2 protein and fibrin were detected with antibodies specific for fgl2 (black arrows) and fibrin (white arrow), respectively.