Bioinformatics analysis of metastasis-related proteins in hepatocellular carcinoma

Table 1 Metastasis-related proteins in HCC

Protein name	IPI number	Ratio1	NO2	Coverage (%)3	Category
Filamin C	IPI00178352	2.49 ± 0.15	2	1.28	Cytoskeleton
Obscurin	IPI00549822	2.91 ± 0.18	2	1.16	Cytoskeleton
Keratin 8	IPI00554648	0.56 ± 0.15	4	25.1	Cytoskeleton
Titin	IPI00179357	1.73 ± 0.12	5	1.11	Cytoskeleton
Plectin 7	IPI00398776	2.49 ± 0.13	2	1.19	Cytoskeleton
MTA2	IPI00171798	0.24 ± 0.11	2	2.69	p53 regulation
Low density lipoprotein receptor-related protein 1 (LRP1)	IPI00020557	0.58 ± 0.15	2	2.27	Cell migration, proliferation, angiogenesis
Mos	IPI00018290	2.86 ± 0.2	2	6.36	Mitoses

¹Ratio calculated as MHCC97H/MHCC97L,

²number of quantified peptides,

³protein coverage calculated as the number of amino acid residues for protein identification divided by the total number of amino acid residues of the protein.