Reduced expression of E-cadherin/catenin complex in hepatocellular carcinomas

Table 3 Relationship between expression of E-cadherin/catenin complex and histological features and clinical parameters in HCCs

		E-cadherin	α-catenin	β-catenin	γ-catenin	p120ctn
	n	+/-	+/-	+/-	+/-	+/-
Histological grade
I-II	23	20/3	19/4	22/1	20/3	19/4
III	58	17/41	11/47	20/38	11/47	15/43
IV	16	3/13	2/14	2/14	3/13	1/15
P		0.000	0.000	0.000	0.000	0.000
Histological stage
I-II	47	24/23	22/25	27/20	25/22	27/20
III	37	12/25	5/32	10/27	10/27	6/31
IV	14	4/10	3/11	5/9	2/12	2/12
P		0.136	0.003	0.017	0.007	0.000
Tumor size
< 3 cm	29	15/14	17/12	18/11	17/12	19/10
3-10 cm	50	18/32	10/40	16/34	13/37	12/38
> 10 cm	18	7/11	5/13	8/10	7/11	4/14
P		0.382	0.002	0.034	0.016	0.000
Capsular invasion
Present	9	7/2	6/3	6/3	5/4	5/4
Absent	88	33/55	26/62	36/52	32/56	30/58
P		0.003	0.055	0.169	0.295	0.277
Satellite nodules
Present	24	10/14	8/16	12/12	7/17	8/16
Absent	73	30/43	24/40	30/43	30/43	27/46
P		1.000	1.000	0.483	0.341	0.811
Vascular invasion
Present	26	8/18	8/18	12/14	10/16	7/19
Absent	71	32/39	24/47	30/41	27/44	28/43
P		0.249	1.000	0.818	1.000	0.341
Lymph node permission
Present	17	4/13	3/14	8/9	6/11	5/12
Absent	80	36/44	29/51	34/46	31/49	30/50
P		0.114	0.116	0.791	1.000	0.59
Intrahepatic metastasis
Present	32	7/25	5/27	9/23	7/25	6/26
Absent	65	33/32	27/38	33/32	30/35	29/36
P		0.008	0.012	0.049	0.026	0.014
AFP-value
< 20 ng/dL	28	6/12	13/15	16/12	14/14	15/13
> 20 ng/dL	69	24/45	19/50	26/43	23/46	20/49
P		0.068	0.096	0.113	0.167	0.035