Neuroendocrine tumors of the gastro-entero-pancreatic system

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Sep 21, 2008 (publication date) through Apr 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2008; 14(35): 5377-5384
Published online Sep 21, 2008. doi: 10.3748/wjg.14.5377

Table 3 Carcinoid syndrome

Clinical features	Incidence (%)	Characteristics	Mediators
Flushing	90	Foregut tumors: prolonged fit, red-purple, localized to face and trunk. Midgut tumors: quick fit, pink-red.	Serotonin, histamine, P substance, prostaglandins
Diarrhea	70	Secretory	Serotonin, histamine, VIP, prostaglandins, gastrin
Abdominal pain	40	Long lasting	Obstruction, hepatomegaly, intestinal ischemia, fibrosis
Profuse sweating	15		Serotonin, histamine
Telangiectasias	25	Face	Unknown cause
Heart disease	30 (right)	Valvulopathies (tricuspid valve, pulmonary valve). Right heart failure. Dyspnea	P substance, serotonin
	10 (left)
Pellagra	5	Dermatitis	Deficit of niacin

Citation: Massironi S, Sciola V, Peracchi M, Ciafardini C, Spampatti MP, Conte D. Neuroendocrine tumors of the gastro-entero-pancreatic system. World J Gastroenterol 2008; 14(35): 5377-5384
URL: https://www.wjgnet.com/1007-9327/full/v14/i35/5377.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5377