Relationship between microvessel count and post-hepatectomy survival in patients with hepatocellular carcinoma

Table 4 Relationship between microvessel density and clinicopathological factors in HCC

	Microvessel count > 178/mm2/ ≤ 178/mm2	P
Pretreatment
No (n = 98)	53/45	1.0
Yes (n = 30)	16/14
Liver damage
A (n = 102)	54/48	0.969
B (n = 26)	15/11
Background liver
Normal liver (n = 7)	3/4	0.459
Chronic hepatitis (n = 75)	38/37
Cirrhosis (n =46)	28/18
Viral status
Hepatitis virus B (n = 50)	32/18	0.152
Hepatitis virus C (n = 61)	31/30
Both hepatitis virus B and C (n = 4)	2/2
Non-B, non-C (n = 13)	4/9
Number of tumors
Solitary (n = 92)	50/42	1.0
Multiple (n =36)	19/17
Tumor size
< 3 cm (n = 31)	15/16	0.371
3-5 cm (n = 49)	24/25
> 5 cm (n = 48)	30/18
Macroscopic finding1
SN (n = 37)	16/21	0.207
SNEG (n = 39)	25/14
CMN (n = 52)	28/24
Vascular involvement
No (n = 83)	42/41	0.476
Yes (n = 45)	27/18
Histopathological differentiation
Well (n = 19)	12/7	0.437
Moderately (n = 97)	55/42
Poorly (n = 6)	2/4
Japan tumor-node-metastasis stage2
I (n = 14)	5/9	0.542
II (n = 51)	27/25
III (n = 44)	25/19
VI-A (n = 19)	12/7
Recurrence
No (n = 32)	16/16	0.386
Yes (n = 96)	53/43

¹Macroscopic classification by Liver Cancer Study Group of Japan[19];

²The General Rules for the Clinical and Pathological Study of Primary Liver Cancer[18]. SN: Single nodular; SNEG: Single nodular with extranodular growth; CMN: Confluent multinodular group.