Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic review

Table 2 The type and frequency of adverse events reported in the 22 studies included in the analysis (n = 1279)

Adverse events	Number of adverse events	Percentage	95% CI
Distention	9	0.70	0.32-1.34
Diarrhea	8	0.63	0.27-1.23
Abdominal pain	6	0.47	0.17-1.02
Constipation	5	0.39	0.13-0.91
Dizziness and sleepiness	4	0.31	0.09-0.80
Headaches	4	0.31	0.09-0.80
Nausea	3	0.23	0.05-0.69
Gastrointestinal discomfort	1	0.08	0.002-0.44
Upper gastrointestinal discomfort	1	0.08	0.002-0.44
Loss of hair	1	0.08	0.002-0.44
Pruritus	1	0.08	0.002-0.44
Paraesthesia	1	0.08	0.002-0.44
Disturbance	1	0.08	0.002-0.44
Hoarseness	1	0.08	0.002-0.44
Shortness of breath and chest pain	1	0.08	0.002-0.44
Total	47	3.67	2.73-4.87