Changes of serum p53 antibodies and clinical significance of radiotherapy for esophageal squamous cell carcinoma

Table 2 Relationship between positive rate of serum p53-Abs and clinical pathophysiological characteristics in EC patients

	n	-	+	Positive (%)	χ2	P
Age (yr)					0.27	0.870
< 50	16	10	6	37.5
≥ 50	30	18	12	40.0
Sex					0.11	0.918
Male	38	23	15	39.5
Female	8	5	3	37.5
TNM stage					6.09	0.014
I+ II	27	21	6	22.2
III + IV	19	8	11	57.9
Histological grade					10.43	0.002
I	15	13	2	13.3
II	17	11	6	35.3
III	14	4	10	71.4
Lymph node metastasis					6.00	0.015
Positive	18	7	11	61.1
Negative	28	21	7	25.0
Size of tumor					2.74	0.102
< 6 cm	32	22	10	31.3
≥ 6 cm	14	6	8	57.1
Site of the tumor					0.02	0.953
Upper thorax	5	3	2	40.0
Middle thorax	21	13	8	38.1
Lower thorax	20	12	8	40.0

TNM: Tumor, nodes and metastasis.