Pathological evolution of hepatitis C virus-“Healthy carriers”

Table 1 Demographic and clinical features of HCV patients with initially normal liver

Demographic and clinical features	Data
Number of patients	76
Sex (M/F)	34/42
Age at the first biopsy (mean, yr)	38 ± 9
Age at Infection (mean, yr)	25 ± 9
BMI (M/F)	23.5 ± 3.1/22 ± 5.1
Route of infection:Transfusion	28 (36.8%)
IVDU	33 (43.4%)
Other or unknown	15 (20%)
Genotype 1/2/3/4/5	40/9/15/6/2
Infection duration, median (95% CI)	13 (1-28)
Times between 2 biopsies, median (95% CI)	4 (2-16)
Alcohol consumption (g/d, mean ± SD)	22.2 ± 44
ALT level between 2 biopsies
Constantly normal	42 (55.3%)
Normal or < 2 N	31 (40.8%)
> 2 N	3 (3.9%)
Viral load:
Low (under 350 000 UI/mL)	33 (55%)
Medium	14 (23.3%)
High (more than 700 000 UI/mL)	13 (21.7%)
Knodell score at the first liver biopsy
Necroinflammatory index (mean ± SD)	1.7 ± 0.7
Fibrosis score (mean ± SD)	0.6 ± 0.5