Adipokines and ghrelin in gastric cancer cachexia

Table 2 Changes in BMI and body weight and baseline biochemical findings (n = 30, mean ± SD)

	Healthy controls (n = 30)	Patients with gastric cancer		P value (between groups) (ANOVA)
		Non-cachexia (n = 30)	Cachexia (n = 30)
Initial BMI (kg/m2)	25.3 ± 2.3	27 ± 5.1	26.3 ± 2.5	0.985
Final BMI (kg/m2)	26.7 ± 2.8	24.8 ± 5.0	20.3 ± 2.5a	0.002
Change BMI (%)	1.26 ± 2.6	-4.0 ± 2.4c	-5.7 ± 5.2a	< 0.001
Initial weight (kg)	75.4 ± 11.0	73.8 ± 13.3	70.0 ± 12.3	0.436
Final weight (kg)	76.2 ± 10.2	70.8 ± 16.3c	53.6 ± 13.0a	0.001
Change weight (kg)	0.15 ± 0.76	-2.9 ± 1.5c	-10.4 ± 3.3a	< 0.001
Hb (gr/L)	12.8 ± 2.8	12.6 ± 1.9	11.1 ± 1.3a	< 0.001
TSH (mIU/mL)	1.96 ± 0.28	1.98 ± 0.85	2.11 ± 0.11	0.492
AST (IU/L)	23.3 ± 8.3	28.7± 8.2	26.5 ± 5.1	0.088
Creatinine (mg/dL)	0.81 ± 0.36	1.03 ± 0.27	0.97 ± 0.28	0.085
WBC (× 109)	6.9 ± 1.2	7.1 ± 2.1	7.0 ± 2.2	0.230
Lymphocytes (%)	22.3 ± 4.2	24.3 ± 3.8	23.98 ± 4.8	0.156

^aP < 0.05 vs healthy controls and non cachexia;

^cP < 0.05 vs healthy controls.